Definition: is a chromosomal change. Most of the information on chromosome rearrangements causing phenotypic or bodily changes and anomalies was obtained as a result of studies of the genotype (gene arrangement in the salivary gland chromosomes) of an ordinary fruit fly. Despite the fact that many human diseases are hereditary in nature, only a small part of them is reliably known that they are caused by chromosomal abnormalities. Only from observations of phenotypic manifestations is it possible to conclude that there have been some changes in genes and chromosomes.
Structural variation in a sentence:
- Structural variation may be a consequence of genetic diseases.
- In a number of cases, the structural variation is a positive phenomenon.
- Structural variations can be diagnosed even before the birth of the child through prenatal studies, such as, for example, amniocentesis or chorionic biopsy, or even after birth with a blood test.
Synonyms and related words: genome, chromosome, genetics, genotype